Cargando…

The c-MYC-ABCB5 axis plays a pivotal role in 5-fluorouracil resistance in human colon cancer cells

c-MYC overexpression is frequently observed in various cancers including colon cancer and regulates many biological activities such as aberrant cell proliferation, apoptosis, genomic instability, immortalization and drug resistance. However, the mechanism by which c-MYC confers drug resistance remai...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kugimiya, Naruji, Nishimoto, Arata, Hosoyama, Tohru, Ueno, Koji, Enoki, Tadahiko, Li, Tao-Sheng, Hamano, Kimikazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511355/ https://www.ncbi.nlm.nih.gov/pubmed/25689483 http://dx.doi.org/10.1111/jcmm.12531

Ejemplares similares

Combinatorial Treatment with Apelin-13 Enhances the Therapeutic Efficacy of a Preconditioned Cell-Based Therapy for Peripheral Ischemia
por: Samura, Makoto, et al.
Publicado: (2016)

Treatment of refractory cutaneous ulcers with mixed sheets consisting of peripheral blood mononuclear cells and fibroblasts
por: Ueno, Koji, et al.
Publicado: (2016)

Therapeutic strategies for cell-based neovascularization in critical limb ischemia
por: Samura, Makoto, et al.
Publicado: (2017)

Increased plasma VEGF levels following ischemic preconditioning are associated with downregulation of miRNA-762 and miR-3072-5p
por: Ueno, Koji, et al.
Publicado: (2016)

Single-Incision Laparoscopic Splenectomy and Splenic Autotransplantation for an Enlarged Wandering Spleen with Torsion
por: Katsura, Shunsaku, et al.
Publicado: (2013)

Influence of aging on the quantity and quality of human cardiac stem cells
por: Nakamura, Tamami, et al.
Publicado: (2016)

Ubiquitin-Specific Protease 22/Silent Information Regulator 1 Axis Plays a Pivotal Role in the Prognosis and 5-Fluorouracil Resistance in Hepatocellular Carcinoma
por: Wen, Xue, et al.
Publicado: (2019)

Development of Novel Mouse Model of Ulcers Induced by Implantation of Magnets
por: Takeuchi, Yuriko, et al.
Publicado: (2017)

A Novel Class of Antitumor Prodrug, 1‐(2′‐Oxopropyl)‐5‐fluorouracil (OFU001), That Releases 5‐Fluorouracil upon Hypoxic Irradiation
por: Shibamoto, Yuta, et al.
Publicado: (2000)

Upregulation of cellular glutathione levels in human ABCB5- and murine Abcb5-transfected cells
por: Kondo, Shingo, et al.
Publicado: (2015)

The Mobilization and Recruitment of C-Kit+ Cells Contribute to Wound Healing after Surgery
por: Takemoto, Yoshihiro, et al.
Publicado: (2012)

The Gravitation of the Moon Plays Pivotal Roles in the Occurrence of the Acute Myocardial Infarction
por: Wake, Ryotaro, et al.
Publicado: (2008)

Smyd5 plays pivotal roles in both primitive and definitive hematopoiesis during zebrafish embryogenesis
por: Fujii, Tomoaki, et al.
Publicado: (2016)

Effects of the Plasma Concentration of 5‐Fluorouracil and the Duration of Continuous Venous Infusion of 5‐Fluorouracil with an Inhibitor of 5‐Fluorouracil Degradation on Yoshida Sarcomas in Rats
por: Fujii, Setsuro, et al.
Publicado: (1989)

The Pivotal Role of Long Noncoding RNA RAB5IF in the Proliferation of Hepatocellular Carcinoma via LGR5 Mediated β-Catenin and c-Myc Signaling
por: Koo, Ja Il, et al.
Publicado: (2019)

ABCB5–ZEB1 Axis Promotes Invasion and Metastasis in Breast Cancer Cells
por: Yao, Juntao, et al.
Publicado: (2017)

Hyperammonemia Secondary to 5-Fluorouracil
por: Scott, Ashley, et al.
Publicado: (2023)

Comparative Antitumor Activity of 5‐Fluorouracil and 5′‐Deoxy‐5‐fluorouridine in Combination with Radiation Therapy in Mice Bearing Colon 26 Adcnocarcinoma
por: Ishikawa, Tohru, et al.
Publicado: (1989)

Pyrotinib Sensitizes 5-Fluorouracil-Resistant HER2(+) Breast Cancer Cells to 5-Fluorouracil
por: Yi, Jianing, et al.
Publicado: (2020)

Radiation- and Photo-induced Activation of 5-Fluorouracil Prodrugs as a Strategy for the Selective Treatment of Solid Tumors
por: Ito, Takeo, et al.
Publicado: (2008)

Efficacy of Topical 5% 5-Fluorouracil with Needling versus 5% 5-Fluorouracil Alone in Stable Vitiligo: A Randomized Controlled Study
por: Zahra, Fatima T., et al.
Publicado: (2020)

Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis
por: Jia, Jiaoyuan, et al.
Publicado: (2020)

Porokeratoma treated with topical 5% 5-fluorouracil cream
por: Li, Steve S., et al.
Publicado: (2021)

Leptin-Notch axis impairs 5-fluorouracil effects on pancreatic cancer
por: Harbuzariu, Adriana, et al.
Publicado: (2018)

Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes.
por: Peters, G. J., et al.
Publicado: (1989)

MicroRNA-34a/EGFR axis plays pivotal roles in lung tumorigenesis
por: Li, Y-L, et al.
Publicado: (2017)

Melanoma Chemotherapy Leads to the Selection of ABCB5-Expressing Cells
por: Chartrain, Marine, et al.
Publicado: (2012)

Elevated expression of ABCB5 in ocular surface squamous neoplasia
por: Jongkhajornpong, Passara, et al.
Publicado: (2016)

Genetic variation in ABCB5 associates with risk of hepatocellular carcinoma
por: Leung, Idy C.‐Y., et al.
Publicado: (2020)

Prokineticin 2 Plays a Pivotal Role in Psoriasis
por: He, Xiaoqin, et al.
Publicado: (2016)

Bioavailability and feasibility of subcutaneous 5-fluorouracil.
por: Borner, M. M., et al.
Publicado: (1993)

5-fluorouracil and cardiotoxicity: a review
por: Sara, Jaskanwal D., et al.
Publicado: (2018)

5-Fluorouracil-induced vasospastic angina
por: Ayyildiz, Orhan, et al.
Publicado: (2005)

5-Fluorouracil Rechallenge After Cardiotoxicity
por: Desai, Aakash, et al.
Publicado: (2020)

Fluorouracil (5-FU)-induced Cardiomyopathy
por: Thalambedu, Nishanth, et al.
Publicado: (2019)

Cardiotoxicities of 5-Fluorouracil and Other Fluoropyrimidines
por: Shiga, Taro, et al.
Publicado: (2020)

5-Fluorouracil–Induced Coronary Vasospasm
por: Arya, Sumedha, et al.
Publicado: (2018)

Efficacy of 5-Fluorouracil in the Treatment of Pterygium
por: Shah, Sobia U, et al.
Publicado: (2021)

5-Fluorouracil Cardiotoxicity: Known But Unknown
por: Brell, Joanna M.
Publicado: (2021)

Oxaliplatin and protracted venous infusion of 5-fluorouracil in patients with advanced or relapsed 5-fluorouracil pretreated colorectal cancer
por: Chau, I, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_r19uivblr016ukef2g41o9bkbu