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HES6 promotes prostate cancer aggressiveness independently of Notch signalling

Notch signalling is implicated in the pathogenesis of a variety of cancers, but its role in prostate cancer is poorly understood. However, selected Notch pathway members are overrepresented in high-grade prostate cancers. We comprehensively profiled Notch pathway components in prostate cells and fou...

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Detalles Bibliográficos
Autores principales: Carvalho, Filipe L F, Marchionni, Luigi, Gupta, Anuj, Kummangal, Basheer A, Schaeffer, Edward M, Ross, Ashley E, Berman, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511360/
https://www.ncbi.nlm.nih.gov/pubmed/25864518
http://dx.doi.org/10.1111/jcmm.12537

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