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Specific inhibition of bile acid transport alters plasma lipids and GLP-1

BACKGROUND: Elobixibat is a minimally absorbed ileal bile acid (BA) transporter (IBAT) inhibitor in development against chronic constipation (CC) and constipation-predominant Irritable Bowel Syndrome (IBS-C). CC is associated with an increased risk for cardiovascular disease and type2 diabetes melli...

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Detalles Bibliográficos
Autores principales:	Rudling, Mats, Camilleri, Michael, Graffner, Hans, Holst, Jens Juul, Rikner, Leif
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511433/ https://www.ncbi.nlm.nih.gov/pubmed/26197999 http://dx.doi.org/10.1186/s12872-015-0070-9

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