Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen

BACKGROUND: Chemical or small interfering (si) RNA screens measure the effects of many independent experimental conditions, each applied to a population of cells (e.g., all of the cells in a well). High-content screens permit a readout (e.g., fluorescence, luminescence, cell morphology) from each ce...

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Detalles Bibliográficos
Autores principales: Gingold, Julian A., Coakley, Ed S., Su, Jie, Lee, Dung-Fang, Lau, Zerlina, Zhou, Hongwei, Felsenfeld, Dan P., Schaniel, Christoph, Lemischka, Ihor R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511455/
https://www.ncbi.nlm.nih.gov/pubmed/26198214
http://dx.doi.org/10.1186/s12859-015-0636-7

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