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Role of membrane Hsp70 in radiation sensitivity of tumor cells

BACKGROUND: The major stress-inducible heat shock protein 70 (Hsp70) is frequently overexpressed in the cytosol and integrated in the plasma membrane of tumor cells via lipid anchorage. Following stress such as non-lethal irradiation Hsp70 synthesis is up-regulated. Intracellular located Hsp70 is kn...

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Detalles Bibliográficos
Autores principales:	Murakami, Naoya, Kühnel, Annett, Schmid, Thomas E., Ilicic, Katarina, Stangl, Stefan, Braun, Isabella S., Gehrmann, Mathias, Molls, Michael, Itami, Jun, Multhoff, Gabriele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511458/ https://www.ncbi.nlm.nih.gov/pubmed/26197988 http://dx.doi.org/10.1186/s13014-015-0461-1

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