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Role of diffuse low-level heteroplasmy of mitochondrial DNA in Alzheimer’s disease neurodegeneration

Alzheimer’s disease (AD) is the most common form of dementia in the elderly. The vast majority of cases are not linked to a known genetic defect and the molecular mechanisms underlying AD pathogenesis are still elusive. Evidence suggests that mitochondrial dysfunction is a prominent feature of the d...

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Detalles Bibliográficos
Autores principales:	Casoli, Tiziana, Spazzafumo, Liana, Di Stefano, Giuseppina, Conti, Fiorenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511837/ https://www.ncbi.nlm.nih.gov/pubmed/26257647 http://dx.doi.org/10.3389/fnagi.2015.00142

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