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Dysregulated Intrahepatic CD4(+) T-Cell Activation Drives Liver Inflammation in Ileitis-Prone SAMP1/YitFc Mice
BACKGROUND & AIMS: Liver inflammation is a common extraintestinal manifestation of inflammatory bowel disease (IBD), but whether liver involvement is a consequence of a primary intestinal defect or results from alternative pathogenic processes remains unclear. Therefore, we sought to determine t...
Autores principales: | Omenetti, Sara, Brogi, Marco, Goodman, Wendy A., Croniger, Colleen M., Eid, Saada, Huang, Alex Y., Laffi, Giacomo, Roskams, Tania, Cominelli, Fabio, Pinzani, Massimo, Pizarro, Theresa T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511857/ https://www.ncbi.nlm.nih.gov/pubmed/26213712 http://dx.doi.org/10.1016/j.jcmgh.2015.05.007 |
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