Cargando…
Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer’s disease
Previous studies have evaluated gene expression in Alzheimer’s disease (AD) brains to identify mechanistic processes, but have been limited by the size of the datasets studied. Here we have implemented a novel meta-analysis approach to identify differentially expressed genes (DEGs) in published data...
Autores principales: | Li, Xinzhong, Long, Jintao, He, Taigang, Belshaw, Robert, Scott, James |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511863/ https://www.ncbi.nlm.nih.gov/pubmed/26202100 http://dx.doi.org/10.1038/srep12393 |
Ejemplares similares
-
Systematic Analysis and Biomarker Study for Alzheimer’s Disease
por: Li, Xinzhong, et al.
Publicado: (2018) -
Discovery of Novel Biomarkers for Alzheimer's Disease from Blood
por: Long, Jintao, et al.
Publicado: (2016) -
Integrated Systems Approach Reveals Sphingolipid Metabolism Pathway Dysregulation in Association with Late-Onset Alzheimer’s Disease
por: Malamon, John Stephen, et al.
Publicado: (2018) -
Identifying genetic interactions associated with late-onset Alzheimer’s disease
por: Floudas, Charalampos S, et al.
Publicado: (2014) -
Somatic mutation that affects transcription factor binding upstream of CD55 in the temporal cortex of a late-onset Alzheimer disease patient
por: Helgadottir, Hafdis T, et al.
Publicado: (2019)