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Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells

Hypoxia which commonly exists in solid tumors, leads to cancer cells chemoresistance via provoking adaptive responses including autophagy. Therefore, we sought to evaluate the role of autophagy and hypoxia as well as the underlying mechanism in the cisplatin resistance of lung cancer cells. Our stud...

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Detalles Bibliográficos
Autores principales: Wu, Hui-Mei, Jiang, Zi-Feng, Ding, Pei-Shan, Shao, Li-Jie, Liu, Rong-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511870/
https://www.ncbi.nlm.nih.gov/pubmed/26201611
http://dx.doi.org/10.1038/srep12291