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Genetic and epigenetic alterations of netrin-1 receptors in gastric cancer with chromosomal instability
BACKGROUND: The gene expressions of netrin-1 dependence receptors, DCC and UNC5C, are frequently downregulated in many cancers. We hypothesized that downregulation of DCC and UNC5C has an important growth regulatory function in gastric tumorigenesis. RESULTS: In the present study, a series of geneti...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511994/ https://www.ncbi.nlm.nih.gov/pubmed/26207151 http://dx.doi.org/10.1186/s13148-015-0096-y |