Genetic and epigenetic alterations of netrin-1 receptors in gastric cancer with chromosomal instability

BACKGROUND: The gene expressions of netrin-1 dependence receptors, DCC and UNC5C, are frequently downregulated in many cancers. We hypothesized that downregulation of DCC and UNC5C has an important growth regulatory function in gastric tumorigenesis. RESULTS: In the present study, a series of geneti...

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Detalles Bibliográficos
Autores principales: Toda, Keisuke, Nagasaka, Takeshi, Umeda, Yuzo, Tanaka, Takehiro, Kawai, Takashi, Fuji, Tomokazu, Taniguchi, Fumitaka, Yasui, Kazuya, Kubota, Nobuhito, Takehara, Yuko, Tazawa, Hiroshi, Kagawa, Shunsuke, Sun, Dong-Sheng, Nishida, Naoshi, Goel, Ajay, Fujiwara, Toshiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511994/
https://www.ncbi.nlm.nih.gov/pubmed/26207151
http://dx.doi.org/10.1186/s13148-015-0096-y

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