Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE(2) in colorectal cancer

BACKGROUND: Misregulation of the PTGS (prostaglandin endoperoxide synthase, also known as cyclooxygenase or COX) pathway may lead to the accumulation of pro-inflammatory signals, which constitutes a hallmark of cancer. To get insight into the role of this signaling pathway in colorectal cancer (CRC)...

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Detalles Bibliográficos
Autores principales: Cebola, Inês, Custodio, Joaquin, Muñoz, Mar, Díez-Villanueva, Anna, Paré, Laia, Prieto, Patricia, Aussó, Susanna, Coll-Mulet, Llorenç, Boscá, Lisardo, Moreno, Victor, Peinado, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512023/
https://www.ncbi.nlm.nih.gov/pubmed/26207152
http://dx.doi.org/10.1186/s13148-015-0110-4

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