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Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway

BACKGROUND: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens. MicroRNAs have been involved in the pathogenesis of different types of cancers, including liver can...

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Detalles Bibliográficos
Autores principales: Drakaki, Alexandra, Hatziapostolou, Maria, Polytarchou, Christos, Vorvis, Christina, Poultsides, George A., Souglakos, John, Georgoulias, Vassilis, Iliopoulos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512159/
https://www.ncbi.nlm.nih.gov/pubmed/26206264
http://dx.doi.org/10.1186/s12885-015-1562-9