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Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway
BACKGROUND: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens. MicroRNAs have been involved in the pathogenesis of different types of cancers, including liver can...
Autores principales: | Drakaki, Alexandra, Hatziapostolou, Maria, Polytarchou, Christos, Vorvis, Christina, Poultsides, George A., Souglakos, John, Georgoulias, Vassilis, Iliopoulos, Dimitrios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512159/ https://www.ncbi.nlm.nih.gov/pubmed/26206264 http://dx.doi.org/10.1186/s12885-015-1562-9 |
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