Cerebellar associative sensory learning defects in five mouse autism models

Sensory integration difficulties have been reported in autism, but their underlying brain-circuit mechanisms are underexplored. Using five autism-related mouse models, Shank3+/ΔC, Mecp2(R308/Y), Cntnap2−/−, L7-Tsc1 (L7/Pcp2(Cre)::Tsc1(flox/+)), and patDp(15q11-13)/+, we report specific perturbations...

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Detalles Bibliográficos
Autores principales: Kloth, Alexander D, Badura, Aleksandra, Li, Amy, Cherskov, Adriana, Connolly, Sara G, Giovannucci, Andrea, Bangash, M Ali, Grasselli, Giorgio, Peñagarikano, Olga, Piochon, Claire, Tsai, Peter T, Geschwind, Daniel H, Hansel, Christian, Sahin, Mustafa, Takumi, Toru, Worley, Paul F, Wang, Samuel S-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512177/
https://www.ncbi.nlm.nih.gov/pubmed/26158416
http://dx.doi.org/10.7554/eLife.06085

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