Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes

Islet autoantibodies detected at disease onset in patients with type 1 diabetes are signs of an autoimmune destruction of the insulin-producing β-cells. To further investigate the genetic determinants of autoantibody positivity, we performed dense immune-focused genotyping on the Immunochip array an...

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Detalles Bibliográficos
Autores principales: Brorsson, Caroline A., Onengut, Suna, Chen, Wei-Min, Wenzlau, Janet, Yu, Liping, Baker, Peter, Williams, Alistair J.K., Bingley, Polly J., Hutton, John C., Eisenbarth, George S., Concannon, Patrick, Rich, Stephen S., Pociot, Flemming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Genetics/Genomes/Proteomics/Metabolomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512221/
https://www.ncbi.nlm.nih.gov/pubmed/25829454
http://dx.doi.org/10.2337/db14-1730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512221/
https://www.ncbi.nlm.nih.gov/pubmed/25829454
http://dx.doi.org/10.2337/db14-1730

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