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Diabetes Limits Stem Cell Mobilization Following G-CSF but Not Plerixafor

Previous studies suggest that diabetes impairs hematopoietic stem cell (HSC) mobilization in response to granulocyte colony-stimulating factor (G-CSF). In this study, we tested whether the CXCR4 antagonist plerixafor, differently from G-CSF, is effective in mobilizing HSCs in patients with diabetes....

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Detalles Bibliográficos
Autores principales: Fadini, Gian Paolo, Fiala, Mark, Cappellari, Roberta, Danna, Marianna, Park, Soo, Poncina, Nicol, Menegazzo, Lisa, Albiero, Mattia, DiPersio, John, Stockerl-Goldstein, Keith, Avogaro, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512229/
https://www.ncbi.nlm.nih.gov/pubmed/25804941
http://dx.doi.org/10.2337/db15-0077