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Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain
The maternal and paternal genomes play different roles in mammalian brains as a result of genomic imprinting, an epigenetic regulation leading to differential expression of the parental alleles of some genes. Here we investigate genomic imprinting in the cerebellum using a newly developed Bayesian s...
Autores principales: | Perez, Julio D, Rubinstein, Nimrod D, Fernandez, Daniel E, Santoro, Stephen W, Needleman, Leigh A, Ho-Shing, Olivia, Choi, John J, Zirlinger, Mariela, Chen, Shau-Kwaun, Liu, Jun S, Dulac, Catherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512258/ https://www.ncbi.nlm.nih.gov/pubmed/26140685 http://dx.doi.org/10.7554/eLife.07860 |
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