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Parasexual Ploidy Reduction Drives Population Heterogeneity Through Random and Transient Aneuploidy in Candida albicans

The opportunistic pathogen Candida albicans has a large repertoire of mechanisms to generate genetic and phenotypic diversity despite the lack of meiosis in its life cycle. Its parasexual cycle enables shifts in ploidy, which in turn facilitate recombination, aneuploidy, and homozygosis of whole chr...

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Detalles Bibliográficos
Autores principales:	Hickman, Meleah A., Paulson, Carsten, Dudley, Aimee, Berman, Judith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2015
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512543/ https://www.ncbi.nlm.nih.gov/pubmed/25991822 http://dx.doi.org/10.1534/genetics.115.178020

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