A Murine Myh6(MerCreMer) Knock-In Allele Specifically Mediates Temporal Genetic Deletion in Cardiomyocytes after Tamoxifen Induction

A mouse model that mediates temporal, specific, and efficient myocardial deletion with Cre-LoxP technology will be a valuable tool to determine the function of genes during heart formation. Mhy6 encodes a cardiac muscle specific protein: alpha-myosin heavy chain. Here, we generated a new Myh6-MerCre...

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Detalles Bibliográficos
Autores principales: Yan, Jianyun, Zhang, Lu, Sultana, Nishat, Park, David S., Shekhar, Akshay, Bu, Lei, Hu, Jun, Razzaque, Shegufta, Cai, Chen-Leng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512710/
https://www.ncbi.nlm.nih.gov/pubmed/26204265
http://dx.doi.org/10.1371/journal.pone.0133472

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