CRISPR-Cas9-Mediated Genome Editing in Leishmania donovani

The prokaryotic CRISPR (clustered regularly interspaced short palindromic repeat)-Cas9, an RNA-guided endonuclease, has been shown to mediate efficient genome editing in a wide variety of organisms. In the present study, the CRISPR-Cas9 system has been adapted to Leishmania donovani, a protozoan par...

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Detalles Bibliográficos
Autores principales: Zhang, Wen-Wei, Matlashewski, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513079/
https://www.ncbi.nlm.nih.gov/pubmed/26199327
http://dx.doi.org/10.1128/mBio.00861-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513079/
https://www.ncbi.nlm.nih.gov/pubmed/26199327
http://dx.doi.org/10.1128/mBio.00861-15

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