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Borane-protected phosphines are redox-active radioprotective agents for endothelial cells

Exposure to radiation can damage endothelial cells in the irradiated area via the production of reactive oxygen species. We synthesized phosphine–borane complexes that reduce disulfide bonds and had previously been shown to interfere with redox-mediated signaling of cell death. We hypothesized that...

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Detalles Bibliográficos
Autores principales: Crowe, Megan E., Lieven, Christopher J., Thompson, Alex F., Sheibani, Nader, Levin, Leonard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513185/
https://www.ncbi.nlm.nih.gov/pubmed/26188467
http://dx.doi.org/10.1016/j.redox.2015.06.015

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