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A long-recommended but seldom-used method of analysis for fall injuries found a unique pattern of risk factors in the youngest-old

BACKGROUND: Few studies on fall risk factors use long-recommended methods for analysis of recurrent events. Previous falls are the biggest risk factor for future falls, but few fall studies focus on the youngest-old. AIMS: This study’s objective was to apply Cox regression for recurrent events to id...

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Autores principales: Legrand, Helen, Pihlsgård, Mats, Nordell, Eva, Elmståhl, Sölve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513192/
https://www.ncbi.nlm.nih.gov/pubmed/25583298
http://dx.doi.org/10.1007/s40520-014-0308-x
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author Legrand, Helen
Pihlsgård, Mats
Nordell, Eva
Elmståhl, Sölve
author_facet Legrand, Helen
Pihlsgård, Mats
Nordell, Eva
Elmståhl, Sölve
author_sort Legrand, Helen
collection PubMed
description BACKGROUND: Few studies on fall risk factors use long-recommended methods for analysis of recurrent events. Previous falls are the biggest risk factor for future falls, but few fall studies focus on the youngest-old. AIMS: This study’s objective was to apply Cox regression for recurrent events to identify factors associated with injurious falls in the youngest-old. METHODS: Participants were community-dwelling residents of southern Sweden (n = 1,133), aged 59–67 at baseline (median 61.2), from the youngest cohorts of the larger Good Aging in Skåne (GÅS) study. Exposure variable data were collected from baseline study visits and medical records. Injurious falls, defined as emergency, inpatient, or specialist visits associated with ICD-10 fall codes during the follow-up period (2001–2011), were gathered from national and regional registries. Analysis was conducted using time to event Cox Regression for recurrent events. RESULTS: A majority (77.1 %) of injurious falls caused serious injuries such as fractures and open wounds. Exposure to nervous system medications [hazard ratio (HR) 1.40, 95 % confidence interval (CI) 1.03–1.89], central nervous system disease (HR 1.79, CI 1.18–2.70), and previous injurious fall(s) (HR 2.00, CI 1.50–2.68) were associated with increased hazard of injurious fall. CONCLUSIONS: Regression for recurrent events is feasible with typical falls’ study data. The association of certain exposures with increased hazard of injurious falls begins earlier than previously studied. Different patterns of risk factors by age can provide insight into the progression of frailty. Tailored fall prevention screening and intervention may be of value in populations younger than those traditionally screened.
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spelling pubmed-45131922015-07-24 A long-recommended but seldom-used method of analysis for fall injuries found a unique pattern of risk factors in the youngest-old Legrand, Helen Pihlsgård, Mats Nordell, Eva Elmståhl, Sölve Aging Clin Exp Res Original Article BACKGROUND: Few studies on fall risk factors use long-recommended methods for analysis of recurrent events. Previous falls are the biggest risk factor for future falls, but few fall studies focus on the youngest-old. AIMS: This study’s objective was to apply Cox regression for recurrent events to identify factors associated with injurious falls in the youngest-old. METHODS: Participants were community-dwelling residents of southern Sweden (n = 1,133), aged 59–67 at baseline (median 61.2), from the youngest cohorts of the larger Good Aging in Skåne (GÅS) study. Exposure variable data were collected from baseline study visits and medical records. Injurious falls, defined as emergency, inpatient, or specialist visits associated with ICD-10 fall codes during the follow-up period (2001–2011), were gathered from national and regional registries. Analysis was conducted using time to event Cox Regression for recurrent events. RESULTS: A majority (77.1 %) of injurious falls caused serious injuries such as fractures and open wounds. Exposure to nervous system medications [hazard ratio (HR) 1.40, 95 % confidence interval (CI) 1.03–1.89], central nervous system disease (HR 1.79, CI 1.18–2.70), and previous injurious fall(s) (HR 2.00, CI 1.50–2.68) were associated with increased hazard of injurious fall. CONCLUSIONS: Regression for recurrent events is feasible with typical falls’ study data. The association of certain exposures with increased hazard of injurious falls begins earlier than previously studied. Different patterns of risk factors by age can provide insight into the progression of frailty. Tailored fall prevention screening and intervention may be of value in populations younger than those traditionally screened. Springer International Publishing 2015-01-14 2015 /pmc/articles/PMC4513192/ /pubmed/25583298 http://dx.doi.org/10.1007/s40520-014-0308-x Text en © The Author(s) 2015 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Article
Legrand, Helen
Pihlsgård, Mats
Nordell, Eva
Elmståhl, Sölve
A long-recommended but seldom-used method of analysis for fall injuries found a unique pattern of risk factors in the youngest-old
title A long-recommended but seldom-used method of analysis for fall injuries found a unique pattern of risk factors in the youngest-old
title_full A long-recommended but seldom-used method of analysis for fall injuries found a unique pattern of risk factors in the youngest-old
title_fullStr A long-recommended but seldom-used method of analysis for fall injuries found a unique pattern of risk factors in the youngest-old
title_full_unstemmed A long-recommended but seldom-used method of analysis for fall injuries found a unique pattern of risk factors in the youngest-old
title_short A long-recommended but seldom-used method of analysis for fall injuries found a unique pattern of risk factors in the youngest-old
title_sort long-recommended but seldom-used method of analysis for fall injuries found a unique pattern of risk factors in the youngest-old
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513192/
https://www.ncbi.nlm.nih.gov/pubmed/25583298
http://dx.doi.org/10.1007/s40520-014-0308-x
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