Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study

To investigate the relationships among fecal isoflavone metabolism, dietary habit and Body Mass Index (BMI), 15 healthy men and 15 healthy women were recruited and provided stool samples for analysis of ex vivo anaerobic incubation of fecal suspension with daidzein. A negative correlation was observ...

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Autores principales: TAMURA, Motoi, HORI, Sachiko, NAKAGAWA, Hiroyuki, KATADA, Kazuhiro, KAMADA, Kazuhiro, UCHIYAMA, Kazuhiko, HANDA, Osamu, TAKAGI, Tomohisa, NAITO, Yuji, YOSHIKAWA, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMFH Press 2015
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513257/
https://www.ncbi.nlm.nih.gov/pubmed/26221577
http://dx.doi.org/10.12938/bmfh.2014-019
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author TAMURA, Motoi
HORI, Sachiko
NAKAGAWA, Hiroyuki
KATADA, Kazuhiro
KAMADA, Kazuhiro
UCHIYAMA, Kazuhiko
HANDA, Osamu
TAKAGI, Tomohisa
NAITO, Yuji
YOSHIKAWA, Toshikazu
author_facet TAMURA, Motoi
HORI, Sachiko
NAKAGAWA, Hiroyuki
KATADA, Kazuhiro
KAMADA, Kazuhiro
UCHIYAMA, Kazuhiko
HANDA, Osamu
TAKAGI, Tomohisa
NAITO, Yuji
YOSHIKAWA, Toshikazu
author_sort TAMURA, Motoi
collection PubMed
description To investigate the relationships among fecal isoflavone metabolism, dietary habit and Body Mass Index (BMI), 15 healthy men and 15 healthy women were recruited and provided stool samples for analysis of ex vivo anaerobic incubation of fecal suspension with daidzein. A negative correlation was observed between BMI and the dihydrodaidzein (DHD) production in men, and between BMI and the equol production in women. There was a positive correlation between intake of soluble dietary fiber and the DHD production in men. The results suggest that dietary habits and BMI are related to the metabolic activity of isoflavonoids by fecal intestinal microbiota.
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spelling pubmed-45132572015-07-28 Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study TAMURA, Motoi HORI, Sachiko NAKAGAWA, Hiroyuki KATADA, Kazuhiro KAMADA, Kazuhiro UCHIYAMA, Kazuhiko HANDA, Osamu TAKAGI, Tomohisa NAITO, Yuji YOSHIKAWA, Toshikazu Biosci Microbiota Food Health Note To investigate the relationships among fecal isoflavone metabolism, dietary habit and Body Mass Index (BMI), 15 healthy men and 15 healthy women were recruited and provided stool samples for analysis of ex vivo anaerobic incubation of fecal suspension with daidzein. A negative correlation was observed between BMI and the dihydrodaidzein (DHD) production in men, and between BMI and the equol production in women. There was a positive correlation between intake of soluble dietary fiber and the DHD production in men. The results suggest that dietary habits and BMI are related to the metabolic activity of isoflavonoids by fecal intestinal microbiota. BMFH Press 2015-05-19 2015 /pmc/articles/PMC4513257/ /pubmed/26221577 http://dx.doi.org/10.12938/bmfh.2014-019 Text en ©2015 BMFH Press http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Note
TAMURA, Motoi
HORI, Sachiko
NAKAGAWA, Hiroyuki
KATADA, Kazuhiro
KAMADA, Kazuhiro
UCHIYAMA, Kazuhiko
HANDA, Osamu
TAKAGI, Tomohisa
NAITO, Yuji
YOSHIKAWA, Toshikazu
Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study
title Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study
title_full Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study
title_fullStr Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study
title_full_unstemmed Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study
title_short Relationships among fecal daidzein metabolites, dietary habit and BMI in healthy volunteers: a preliminary study
title_sort relationships among fecal daidzein metabolites, dietary habit and bmi in healthy volunteers: a preliminary study
topic Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513257/
https://www.ncbi.nlm.nih.gov/pubmed/26221577
http://dx.doi.org/10.12938/bmfh.2014-019
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