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Unfolding Kinetics of the Human Telomere i-Motif Under a 10 pN Force Imposed by the α-Hemolysin Nanopore Identify Transient Folded-State Lifetimes at Physiological pH

[Image: see text] Cytosine (C)-rich DNA can adopt i-motif folds under acidic conditions, with the human telomere i-motif providing a well-studied example. The dimensions of this i-motif are appropriate for capture in the nanocavity of the α-hemolysin (α-HL) protein pore under an electrophoretic forc...

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Detalles Bibliográficos
Autores principales:	Ding, Yun, Fleming, Aaron M., He, Lidong, Burrows, Cynthia J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513840/ https://www.ncbi.nlm.nih.gov/pubmed/26110559 http://dx.doi.org/10.1021/jacs.5b03912

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