A fine balance: epigenetic control of cellular quiescence by the tumor suppressor PRDM2/RIZ at a bivalent domain in the cyclin a gene

Adult stem cell quiescence is critical to ensure regeneration while minimizing tumorigenesis. Epigenetic regulation contributes to cell cycle control and differentiation, but few regulators of the chromatin state in quiescent cells are known. Here we report that the tumor suppressor PRDM2/RIZ, an H3...

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Detalles Bibliográficos
Autores principales: Cheedipudi, Sirisha, Puri, Deepika, Saleh, Amena, Gala, Hardik P., Rumman, Mohammed, Pillai, Malini S., Sreenivas, Prethish, Arora, Reety, Sellathurai, Jeeva, Schrøder, Henrik Daa, Mishra, Rakesh K., Dhawan, Jyotsna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513853/
https://www.ncbi.nlm.nih.gov/pubmed/26040698
http://dx.doi.org/10.1093/nar/gkv567

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