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Functional VEGFA knockdown with artificial 3′-tailed mirtrons defined by 5′ splice site and branch point

Mirtrons are introns that form pre-miRNA hairpins after splicing to produce RNA interference (RNAi) effectors distinct from Drosha-dependent intronic miRNAs, and will be especially useful for co-delivery of coding genes and RNAi. A specific family of mirtrons – 3′-tailed mirtrons – has hairpins prec...

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Detalles Bibliográficos
Autores principales:	Kock, Kian Hong, Kong, Kiat Whye, Hoon, Shawn, Seow, Yiqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513878/ https://www.ncbi.nlm.nih.gov/pubmed/26089392 http://dx.doi.org/10.1093/nar/gkv617

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