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Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes
Recent studies showed that Rai1 and its homologs are a crucial component of the mRNA 5′-end capping quality control mechanism. They can possess RNA 5′-end pyrophosphohydrolase (PPH), decapping, and 5′-3′ exonuclease (toward 5′ monophosphate RNA) activities, which help to degrade mRNAs with incomplet...
Autores principales: | Wang, Vivien Ya-Fan, Jiao, Xinfu, Kiledjian, Megerditch, Tong, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513879/ https://www.ncbi.nlm.nih.gov/pubmed/26101253 http://dx.doi.org/10.1093/nar/gkv620 |
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