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Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes

Recent studies showed that Rai1 and its homologs are a crucial component of the mRNA 5′-end capping quality control mechanism. They can possess RNA 5′-end pyrophosphohydrolase (PPH), decapping, and 5′-3′ exonuclease (toward 5′ monophosphate RNA) activities, which help to degrade mRNAs with incomplet...

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Detalles Bibliográficos
Autores principales:	Wang, Vivien Ya-Fan, Jiao, Xinfu, Kiledjian, Megerditch, Tong, Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513879/ https://www.ncbi.nlm.nih.gov/pubmed/26101253 http://dx.doi.org/10.1093/nar/gkv620

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