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Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology
Genetic and molecular studies have confirmed the central role of amyloid-β production and fibrillation in the pathogenesis of Alzheimer's disease (AD). However, the pathological pathways from amyloid-β peptide oligomerization to the major pathological hallmarks of AD, such as neurofibrillary ta...
Autores principales: | Salminen, Antero, Ojala, Johanna, Suuronen, Tiina, Kaarniranta, Kai, Kauppinen, Anu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514104/ https://www.ncbi.nlm.nih.gov/pubmed/18793350 http://dx.doi.org/10.1111/j.1582-4934.2008.00496.x |
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