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CpG oligodeoxynucleotides as mucosal adjuvants

Bacterial DNA comprising palindromic sequences and containing unmethylated CpG is recognized by toll-like receptor 9 of plasmacytoid dendritic cells (pDCs) and induces the production of interferon-α and chemokines, leading to the activation of a Th1 immune response. Therefore, synthetic equivalents...

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Detalles Bibliográficos
Autores principales:	Iho, Sumiko, Maeyama, Jun-ichi, Suzuki, Fumiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514178/ https://www.ncbi.nlm.nih.gov/pubmed/25751765 http://dx.doi.org/10.1080/21645515.2014.1004033

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