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Characterization of a recombinant humanized anti-cocaine monoclonal antibody and its Fab fragment

Variations of post-translational modifications are important for stability and in vivo behavior of therapeutic antibodies. A recombinant humanized anti-cocaine monoclonal antibody (h2E2) was characterized for heterogeneity of N-linked glycosylation and disulfide bonds. In addition, charge heterogene...

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Detalles Bibliográficos
Autores principales:	Kirley, Terence L, Norman, Andrew B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	PASSIVE VACCINATION/Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514192/ https://www.ncbi.nlm.nih.gov/pubmed/25692880 http://dx.doi.org/10.4161/21645515.2014.990856

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