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Impact of universal vaccination against varicella in Italy: Experiences from eight Italian Regions

In Italy, the introduction of Universal Varicella Vaccination (UVV) has been decided but postponed, as a national programme, until 2015, when data from Regions which have already implemented it will be available. Starting from 2003, eight Italian Regions (Basilicata, Calabria, Friuli Venezia Giulia,...

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Autores principales: Bechini, Angela, Boccalini, Sara, Baldo, Vincenzo, Cocchio, Silvia, Castiglia, Paolo, Gallo, Tolinda, Giuffrida, Sandro, Locuratolo, Francesco, Tafuri, Silvio, Martinelli, Domenico, Prato, Rosa, Amodio, Emanuele, Vitale, Francesco, Bonanni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514224/
https://www.ncbi.nlm.nih.gov/pubmed/25483517
http://dx.doi.org/10.4161/hv.34311
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author Bechini, Angela
Boccalini, Sara
Baldo, Vincenzo
Cocchio, Silvia
Castiglia, Paolo
Gallo, Tolinda
Giuffrida, Sandro
Locuratolo, Francesco
Tafuri, Silvio
Martinelli, Domenico
Prato, Rosa
Amodio, Emanuele
Vitale, Francesco
Bonanni, Paolo
author_facet Bechini, Angela
Boccalini, Sara
Baldo, Vincenzo
Cocchio, Silvia
Castiglia, Paolo
Gallo, Tolinda
Giuffrida, Sandro
Locuratolo, Francesco
Tafuri, Silvio
Martinelli, Domenico
Prato, Rosa
Amodio, Emanuele
Vitale, Francesco
Bonanni, Paolo
author_sort Bechini, Angela
collection PubMed
description In Italy, the introduction of Universal Varicella Vaccination (UVV) has been decided but postponed, as a national programme, until 2015, when data from Regions which have already implemented it will be available. Starting from 2003, eight Italian Regions (Basilicata, Calabria, Friuli Venezia Giulia, Apulia, Sardinia, Sicily, Tuscany and Veneto) have progressively introduced UVV, in their immunization programme, with different schedules in children aged 13–15 months and 5–6 years, currently a two-dose schedule is adopted by all Regions. In June 2013, an Interregional Group on Varicella Vaccination (IGVV) has been established in order to assess the effectiveness of varicella vaccination with standardized and shared tools. The aim of this study was to evaluate the impact of varicella vaccination on the incidence and hospitalizations due to varicella and its complications in the period 2003–2012 in order to support the Italian decision makers on the future national adoption. Preliminary data showed that a general reduction of incidence and hospitalization rates was observed in the study period, resulting in relevant savings for the National Health Service. Immunization coverage with first dose at 24 months of age was high in all Regions (84%–95%) in 2012. Adverse events due to varicella vaccines were rare and without permanent sequelae. Underreporting of varicella cases and delays in the administration of the first dose of varicella vaccines were the main critical issues. In conclusion, solid evidences in support of universal UVV arise from the experiences available today in Italy.
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spelling pubmed-45142242015-09-14 Impact of universal vaccination against varicella in Italy: Experiences from eight Italian Regions Bechini, Angela Boccalini, Sara Baldo, Vincenzo Cocchio, Silvia Castiglia, Paolo Gallo, Tolinda Giuffrida, Sandro Locuratolo, Francesco Tafuri, Silvio Martinelli, Domenico Prato, Rosa Amodio, Emanuele Vitale, Francesco Bonanni, Paolo Hum Vaccin Immunother Research Paper In Italy, the introduction of Universal Varicella Vaccination (UVV) has been decided but postponed, as a national programme, until 2015, when data from Regions which have already implemented it will be available. Starting from 2003, eight Italian Regions (Basilicata, Calabria, Friuli Venezia Giulia, Apulia, Sardinia, Sicily, Tuscany and Veneto) have progressively introduced UVV, in their immunization programme, with different schedules in children aged 13–15 months and 5–6 years, currently a two-dose schedule is adopted by all Regions. In June 2013, an Interregional Group on Varicella Vaccination (IGVV) has been established in order to assess the effectiveness of varicella vaccination with standardized and shared tools. The aim of this study was to evaluate the impact of varicella vaccination on the incidence and hospitalizations due to varicella and its complications in the period 2003–2012 in order to support the Italian decision makers on the future national adoption. Preliminary data showed that a general reduction of incidence and hospitalization rates was observed in the study period, resulting in relevant savings for the National Health Service. Immunization coverage with first dose at 24 months of age was high in all Regions (84%–95%) in 2012. Adverse events due to varicella vaccines were rare and without permanent sequelae. Underreporting of varicella cases and delays in the administration of the first dose of varicella vaccines were the main critical issues. In conclusion, solid evidences in support of universal UVV arise from the experiences available today in Italy. Taylor & Francis 2014-08-06 /pmc/articles/PMC4514224/ /pubmed/25483517 http://dx.doi.org/10.4161/hv.34311 Text en Copyright © 2015 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Research Paper
Bechini, Angela
Boccalini, Sara
Baldo, Vincenzo
Cocchio, Silvia
Castiglia, Paolo
Gallo, Tolinda
Giuffrida, Sandro
Locuratolo, Francesco
Tafuri, Silvio
Martinelli, Domenico
Prato, Rosa
Amodio, Emanuele
Vitale, Francesco
Bonanni, Paolo
Impact of universal vaccination against varicella in Italy: Experiences from eight Italian Regions
title Impact of universal vaccination against varicella in Italy: Experiences from eight Italian Regions
title_full Impact of universal vaccination against varicella in Italy: Experiences from eight Italian Regions
title_fullStr Impact of universal vaccination against varicella in Italy: Experiences from eight Italian Regions
title_full_unstemmed Impact of universal vaccination against varicella in Italy: Experiences from eight Italian Regions
title_short Impact of universal vaccination against varicella in Italy: Experiences from eight Italian Regions
title_sort impact of universal vaccination against varicella in italy: experiences from eight italian regions
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514224/
https://www.ncbi.nlm.nih.gov/pubmed/25483517
http://dx.doi.org/10.4161/hv.34311
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