Cargando…
Acute multiple focal neuropathies and delayed postanoxic encephalopathy after alcohol intoxication
Acute-onset alcohol-associated neuropathy is only occasionally reported, and delayed postanoxic encephalopathy is rare. Here, we report a male who developed acute multiple focal neuropathies and later delayed postanoxic encephalopathy after alcohol intoxication. He had hypoxia and rhabdomyolysis, pr...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514315/ https://www.ncbi.nlm.nih.gov/pubmed/26229472 http://dx.doi.org/10.2147/NDT.S87731 |
_version_ | 1782382754999042048 |
---|---|
author | Wang, Wei-Che Yang, Hsiu-Chun Chen, Yao-Jen |
author_facet | Wang, Wei-Che Yang, Hsiu-Chun Chen, Yao-Jen |
author_sort | Wang, Wei-Che |
collection | PubMed |
description | Acute-onset alcohol-associated neuropathy is only occasionally reported, and delayed postanoxic encephalopathy is rare. Here, we report a male who developed acute multiple focal neuropathies and later delayed postanoxic encephalopathy after alcohol intoxication. He had hypoxia and rhabdomyolysis, presenting with acute renal failure initially, and cardiopulmonary support, including mechanical ventilation, led to improvement of the patient at the acute stage. He suffered from bilateral hand numbness and mild weakness of the right lower limb thereafter. Nerve-conduction study revealed no pickup of compound muscle action potential or sensory nerve action potential in the bilateral ulnar nerve, but showed attenuated amplitude of compound muscle action potential in the right femoral nerve. Multiple focal neuropathies were suspected, and he received outpatient rehabilitation after being discharged. However, the patient developed gradual onset of weakness in four limbs and cognitive impairment 23 days after the hypoxia event. Brain computed tomography showed low attenuation over bilateral globus pallidus, and brain magnetic resonance imaging disclosed diffuse increased signal intensity on T(2)-weighted images and fluid-attenuated inversion recovery in bilateral white matter. He was admitted again under the impression of delayed postanoxic brain injury. Supportive treatment and active rehabilitation were given. He had gradual improvement in motor and functional status after rehabilitation. He could walk with festinating gait under supervision, and needed only minimal assistance in performing activities of daily living approximately 1 year later. |
format | Online Article Text |
id | pubmed-4514315 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-45143152015-07-30 Acute multiple focal neuropathies and delayed postanoxic encephalopathy after alcohol intoxication Wang, Wei-Che Yang, Hsiu-Chun Chen, Yao-Jen Neuropsychiatr Dis Treat Case Report Acute-onset alcohol-associated neuropathy is only occasionally reported, and delayed postanoxic encephalopathy is rare. Here, we report a male who developed acute multiple focal neuropathies and later delayed postanoxic encephalopathy after alcohol intoxication. He had hypoxia and rhabdomyolysis, presenting with acute renal failure initially, and cardiopulmonary support, including mechanical ventilation, led to improvement of the patient at the acute stage. He suffered from bilateral hand numbness and mild weakness of the right lower limb thereafter. Nerve-conduction study revealed no pickup of compound muscle action potential or sensory nerve action potential in the bilateral ulnar nerve, but showed attenuated amplitude of compound muscle action potential in the right femoral nerve. Multiple focal neuropathies were suspected, and he received outpatient rehabilitation after being discharged. However, the patient developed gradual onset of weakness in four limbs and cognitive impairment 23 days after the hypoxia event. Brain computed tomography showed low attenuation over bilateral globus pallidus, and brain magnetic resonance imaging disclosed diffuse increased signal intensity on T(2)-weighted images and fluid-attenuated inversion recovery in bilateral white matter. He was admitted again under the impression of delayed postanoxic brain injury. Supportive treatment and active rehabilitation were given. He had gradual improvement in motor and functional status after rehabilitation. He could walk with festinating gait under supervision, and needed only minimal assistance in performing activities of daily living approximately 1 year later. Dove Medical Press 2015-07-17 /pmc/articles/PMC4514315/ /pubmed/26229472 http://dx.doi.org/10.2147/NDT.S87731 Text en © 2015 Wang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Case Report Wang, Wei-Che Yang, Hsiu-Chun Chen, Yao-Jen Acute multiple focal neuropathies and delayed postanoxic encephalopathy after alcohol intoxication |
title | Acute multiple focal neuropathies and delayed postanoxic encephalopathy after alcohol intoxication |
title_full | Acute multiple focal neuropathies and delayed postanoxic encephalopathy after alcohol intoxication |
title_fullStr | Acute multiple focal neuropathies and delayed postanoxic encephalopathy after alcohol intoxication |
title_full_unstemmed | Acute multiple focal neuropathies and delayed postanoxic encephalopathy after alcohol intoxication |
title_short | Acute multiple focal neuropathies and delayed postanoxic encephalopathy after alcohol intoxication |
title_sort | acute multiple focal neuropathies and delayed postanoxic encephalopathy after alcohol intoxication |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514315/ https://www.ncbi.nlm.nih.gov/pubmed/26229472 http://dx.doi.org/10.2147/NDT.S87731 |
work_keys_str_mv | AT wangweiche acutemultiplefocalneuropathiesanddelayedpostanoxicencephalopathyafteralcoholintoxication AT yanghsiuchun acutemultiplefocalneuropathiesanddelayedpostanoxicencephalopathyafteralcoholintoxication AT chenyaojen acutemultiplefocalneuropathiesanddelayedpostanoxicencephalopathyafteralcoholintoxication |