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Chromatin segmentation based on a probabilistic model for read counts explains a large portion of the epigenome
Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is an increasingly common experimental approach to generate genome-wide maps of histone modifications and to dissect the complexity of the epigenome. Here, we propose EpiCSeg: a novel algorithm that combines several histone modification...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514447/ https://www.ncbi.nlm.nih.gov/pubmed/26206277 http://dx.doi.org/10.1186/s13059-015-0708-z |