Chlamydia trachomatis In Vivo to In Vitro Transition Reveals Mechanisms of Phase Variation and Down-Regulation of Virulence Factors

Research on the obligate intracellular bacterium Chlamydia trachomatis demands culture in cell-lines, but the adaptive process behind the in vivo to in vitro transition is not understood. We assessed the genomic and transcriptomic dynamics underlying C. trachomatis in vitro adaptation of strains rep...

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Detalles Bibliográficos
Autores principales: Borges, Vítor, Pinheiro, Miguel, Antelo, Minia, Sampaio, Daniel A., Vieira, Luís, Ferreira, Rita, Nunes, Alexandra, Almeida, Filipe, Mota, Luís J., Borrego, Maria J., Gomes, João P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514472/
https://www.ncbi.nlm.nih.gov/pubmed/26207372
http://dx.doi.org/10.1371/journal.pone.0133420

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