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Botulinum Neurotoxins Can Enter Cultured Neurons Independent of Synaptic Vesicle Recycling
Botulinum neurotoxins (BoNTs) are the causative agent of the severe and long-lasting disease botulism. At least seven different serotypes of BoNTs (denoted A-G) have been described. All BoNTs enter human or animal neuronal cells via receptor mediated endocytosis and cleave cytosolic SNARE proteins,...
Autores principales: | Pellett, Sabine, Tepp, William H., Scherf, Jacob M., Johnson, Eric A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514655/ https://www.ncbi.nlm.nih.gov/pubmed/26207366 http://dx.doi.org/10.1371/journal.pone.0133737 |
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