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Association Study of Mannose-Binding Lectin Levels and Genetic Variants in Lectin Pathway Proteins with Susceptibility to Age-Related Macular Degeneration: A Case-Control Study

BACKGROUND: In age-related macular degeneration (AMD) the complement system is thought to be activated by chronic oxidative damage with genetic variants identified in the alternative pathway as susceptibility factors. However, the involvement of the lectin pathway of complement, a key mediator of ox...

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Detalles Bibliográficos
Autores principales:	Osthoff, Michael, Dean, Melinda M., Baird, Paul N., Richardson, Andrea J., Daniell, Mark, Guymer, Robyn H., Eisen, Damon P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514807/ https://www.ncbi.nlm.nih.gov/pubmed/26207622 http://dx.doi.org/10.1371/journal.pone.0134107

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