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Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection

Protective antigen (PA), one of the components of the anthrax toxin, is the major component of human anthrax vaccine (Biothrax). Human anthrax vaccines approved in the United States and Europe consist of an alum-adsorbed or precipitated (respectively) supernatant material derived from cultures of to...

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Detalles Bibliográficos
Autores principales: Reed, Matthew D., Wilder, Julie A., Mega, William M., Hutt, Julie A., Kuehl, Philip J., Valderas, Michelle W., Chew, Lawrence L., Liang, Bertrand C., Squires, Charles H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514824/
https://www.ncbi.nlm.nih.gov/pubmed/26207820
http://dx.doi.org/10.1371/journal.pone.0130952