Comparison of Bile Acids and Acetaminophen Protein Adducts in Children and Adolescents with Acetaminophen Toxicity

Metabolomics approaches have enabled the study of new mechanisms of liver injury in experimental models of drug toxicity. Disruption of bile acid homeostasis is a known mechanism of drug induced liver injury. The relationship of individual bile acids to indicators of oxidative drug metabolism (aceta...

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Detalles Bibliográficos
Autores principales: James, Laura, Yan, Ke, Pence, Lisa, Simpson, Pippa, Bhattacharyya, Sudeepa, Gill, Pritmohinder, Letzig, Lynda, Kearns, Gregory, Beger, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514842/
https://www.ncbi.nlm.nih.gov/pubmed/26208104
http://dx.doi.org/10.1371/journal.pone.0131010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514842/
https://www.ncbi.nlm.nih.gov/pubmed/26208104
http://dx.doi.org/10.1371/journal.pone.0131010

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