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Precore/Core Region Mutations in Hepatitis B Virus DNA Predict Postoperative Survival in Hepatocellular Carcinoma

Hepatitis B virus (HBV) DNA is prone to mutations because of the proofreading deficiencies of HBV polymerase. We have identified hepatocellular carcinoma (HCC) survival-associated HBV mutations in the X protein region of HBV DNA. In the present study, we extend our research to assess HCC survival-as...

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Detalles Bibliográficos
Autores principales: Xie, Ying, Liu, Shufeng, Zhao, Yufei, Zhang, Lan, Zhao, Yue, Liu, Binghui, Guo, Zhanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514880/
https://www.ncbi.nlm.nih.gov/pubmed/26208136
http://dx.doi.org/10.1371/journal.pone.0133393