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A statistical physics perspective on alignment-independent protein sequence comparison

Motivation: Within bioinformatics, the textual alignment of amino acid sequences has long dominated the determination of similarity between proteins, with all that implies for shared structure, function and evolutionary descent. Despite the relative success of modern-day sequence alignment algorithm...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Amit K., Nasiev, Diar, Flower, Darren R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514925/
https://www.ncbi.nlm.nih.gov/pubmed/25810434
http://dx.doi.org/10.1093/bioinformatics/btv167