Cargando…

Development of patent Litomosoides sigmodontis infections in semi-susceptible C57BL/6 mice in the absence of adaptive immune responses

BACKGROUND: One of the most advantageous research aspects of the murine model of filariasis, Litomosoides sigmodontis, is the availability of mouse strains with varying susceptibility to the nematode infection. In C57BL/6 mice, L. sigmodontis worms are largely eliminated in this strain by day 40 pos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Layland, Laura E., Ajendra, Jesuthas, Ritter, Manuel, Wiszniewsky, Anna, Hoerauf, Achim, Hübner, Marc P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514938/ https://www.ncbi.nlm.nih.gov/pubmed/26209319 http://dx.doi.org/10.1186/s13071-015-1011-2

Ejemplares similares

Absence of IL-17A in Litomosoides sigmodontis-infected mice influences worm development and drives elevated filarial-specific IFN-γ
por: Ritter, Manuel, et al.
Publicado: (2018)

Human filariasis—contributions of the Litomosoides sigmodontis and Acanthocheilonema viteae animal model
por: Risch, Frederic, et al.
Publicado: (2021)

NOD2 dependent neutrophil recruitment is required for early protective immune responses against infectious Litomosoides sigmodontis L3 larvae
por: Ajendra, Jesuthas, et al.
Publicado: (2016)

Potential of Nucleic Acid Receptor Ligands to Improve Vaccination Efficacy against the Filarial Nematode Litomosoides sigmodontis
por: Scheunemann, Johanna F., et al.
Publicado: (2023)

The efficacy of the benzimidazoles oxfendazole and flubendazole against Litomosoides sigmodontis is dependent on the adaptive and innate immune system
por: Risch, Frederic, et al.
Publicado: (2023)

Adoptive Transfer of Immune Cells Into RAG2IL-2Rγ-Deficient Mice During Litomosoides sigmodontis Infection: A Novel Approach to Investigate Filarial-Specific Immune Responses
por: Wiszniewsky, Anna, et al.
Publicado: (2021)

ILC2s Control Microfilaremia During Litomosoides sigmodontis Infection in Rag2(-/-) Mice
por: Reichwald, Julia J., et al.
Publicado: (2022)

Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds
por: Hübner, Marc P., et al.
Publicado: (2019)

Combinations of registered drugs reduce treatment times required to deplete Wolbachia in the Litomosoides sigmodontis mouse model
por: Specht, Sabine, et al.
Publicado: (2018)

Susceptibility to L. sigmodontis infection is highest in animals lacking IL-4R/IL-5 compared to single knockouts of IL-4R, IL-5 or eosinophils
por: Frohberger, Stefan J., et al.
Publicado: (2019)

In vivo efficacy of the boron-pleuromutilin AN11251 against Wolbachia of the rodent filarial nematode Litomosoides sigmodontis
por: Ehrens, Alexandra, et al.
Publicado: (2020)

Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models
por: Hübner, Marc P., et al.
Publicado: (2019)

Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro
por: Hübner, Marc P., et al.
Publicado: (2020)

Lipid profiling of the filarial nematodes Onchocerca volvulus, Onchocerca ochengi and Litomosoides sigmodontis reveals the accumulation of nematode-specific ether phospholipids in the host
por: Wewer, Vera, et al.
Publicado: (2017)

The Chemokine CXCL12 Is Essential for the Clearance of the Filaria Litomosoides sigmodontis in Resistant Mice
por: Bouchery, Tiffany, et al.
Publicado: (2012)

Limited role of mast cells during infection with the parasitic nematode Litomosoides sigmodontis
por: Linnemann, Lara Christine, et al.
Publicado: (2020)

Comparative analysis of small RNAs released by the filarial nematode Litomosoides sigmodontis in vitro and in vivo
por: Quintana, Juan F., et al.
Publicado: (2019)

S100A8/S100A9 deficiency increases neutrophil activation and protective immune responses against invading infective L3 larvae of the filarial nematode Litomosoides sigmodontis
por: Frohberger, Stefan J., et al.
Publicado: (2020)

Unbalanced Arginine pathway and altered maturation of pleural macrophages in Th2-deficient mice during Litomosoides sigmodontis filarial infection
por: Remion, Estelle, et al.
Publicado: (2022)

Differential tissular distribution of Litomosoides sigmodontis microfilariae between microfilaremic and amicrofilaremic mice following experimental infection
por: Bouchery, T., et al.
Publicado: (2012)

The immune response of inbred laboratory mice to Litomosoides sigmodontis: A route to discovery in myeloid cell biology
por: Finlay, Conor M., et al.
Publicado: (2020)

Co-infection restrains Litomosoides sigmodontis filarial load and plasmodial P. yoelii but not P. chabaudi parasitaemia in mice
por: Karadjian, Gregory, et al.
Publicado: (2014)

TGFβ depletion does neither modulate acute E. coli-induced inflammatory immune responses nor impair the protective effect by chronic filarial infection
por: Buerfent, Benedikt C., et al.
Publicado: (2019)

Concurrent Infection With the Filarial Helminth Litomosoides sigmodontis Attenuates or Worsens Influenza A Virus Pathogenesis in a Stage-Dependent Manner
por: Hardisty, Gareth R., et al.
Publicado: (2022)

Fitness Cost of Litomosoides sigmodontis Filarial Infection in Mite Vectors; Implications of Infected Haematophagous Arthropod Excretory Products in Host-Vector Interactions
por: Nieguitsila, Adélaïde, et al.
Publicado: (2013)

Migratory phase of Litomosoides sigmodontis filarial infective larvae is associated with pathology and transient increase of S100A9 expressing neutrophils in the lung
por: Karadjian, Gregory, et al.
Publicado: (2017)

Chronic Filarial Infection Provides Protection against Bacterial Sepsis by Functionally Reprogramming Macrophages
por: Gondorf, Fabian, et al.
Publicado: (2015)

Immunization with L. sigmodontis Microfilariae Reduces Peripheral Microfilaraemia after Challenge Infection by Inhibition of Filarial Embryogenesis
por: Ziewer, Sebastian, et al.
Publicado: (2012)

In vivo kinetics of Wolbachia depletion by ABBV-4083 in L. sigmodontis adult worms and microfilariae
por: Hübner, Marc P., et al.
Publicado: (2019)

ST2 Deficiency Does Not Impair Type 2 Immune Responses during Chronic Filarial Infection but Leads to an Increased Microfilaremia Due to an Impaired Splenic Microfilarial Clearance
por: Ajendra, Jesuthas, et al.
Publicado: (2014)

Reduced Type 2 Innate Lymphocyte Cell Frequencies in Patent Wuchereria bancrofti-Infected Individuals
por: Tamadaho, Ruth S. E., et al.
Publicado: (2023)

Helminths and their implication in sepsis – a new branch of their immunomodulatory behaviour?
por: Hübner, Marc P, et al.
Publicado: (2013)

STUDIES ON THE METABOLISM OF THE FILARIAL WORM, LITOMOSOIDES CARINII
por: Bueding, Ernest
Publicado: (1949)

Distinct Immune Profiles of Exhausted Effector and Memory CD8(+) T Cells in Individuals With Filarial Lymphedema
por: Horn, Sacha, et al.
Publicado: (2021)

Filarial Lymphedema Patients Are Characterized by Exhausted CD4(+) T Cells
por: Horn, Sacha, et al.
Publicado: (2022)

Identification and ultrastructural characterization of the Wolbachia symbiont in Litomosoides chagasfilhoi
por: Chagas-Moutinho, Vanessa Aparecida, et al.
Publicado: (2015)

Differences in susceptibility to ADR nephropathy among C57BL/6 substrains
por: Watanabe, Masaki, et al.
Publicado: (2023)

C57BL/6J and C57BL/6NJ Mice Are Differentially Susceptible to Inflammation-Associated Disease Caused by Influenza A Virus
por: Eisfeld, Amie J., et al.
Publicado: (2019)

Multivariable Regression Analysis in Schistosoma mansoni-Infected Individuals in the Sudan Reveals Unique Immunoepidemiological Profiles in Uninfected, egg+ and Non-egg+ Infected Individuals
por: Elfaki, Tayseer Elamin Mohamed, et al.
Publicado: (2016)

Absence of a secondary glucocorticoid response in C57BL/6J mice treated with topical dexamethasone
por: Faralli, Jennifer A., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_v9h1ock3vfr90l4f3fn5uqmmcq