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Cdc7 overexpression is an independent prognostic marker and a potential therapeutic target in colorectal cancer

BACKGROUND: Cdc7 is a widely expressed protein kinase implicated in cell division, cell cycle checkpoint mechanisms and cancer progression. Recently, it has been suggested as a target for anti-cancer therapy. METHODS: To determine the relationship of Cdc7 protein expression with tumor phenotype, mol...

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Detalles Bibliográficos
Autores principales:	Melling, Nathaniel, Muth, Johanna, Simon, Ronald, Bokemeyer, Carsten, Terracciano, Luigi, Sauter, Guido, Izbicki, Jakob Robert, Marx, Andreas Holger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514957/ https://www.ncbi.nlm.nih.gov/pubmed/26208856 http://dx.doi.org/10.1186/s13000-015-0360-7

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