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Overexpression of MALT1-A20-NF-κB in adult B-cell acute lymphoblastic leukemia
BACKGROUND: A20 is a dual inhibitor of NF-κB activation and apoptosis in the tumor necrosis factor receptor 1 signaling pathway, and both are related to tumorigenesis. A20 is frequently inactivated by deletions and/or mutations in several B and T cell lymphoma subtypes; however, knowledge of the rol...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514975/ https://www.ncbi.nlm.nih.gov/pubmed/26213496 http://dx.doi.org/10.1186/s12935-015-0222-0 |