Cargando…

GTSE1 expression represses apoptotic signaling and confers cisplatin resistance in gastric cancer cells

BACKGROUND: Platinum based therapy is commonly used in the treatment of advanced gastric cancer. However, resistance to chemotherapy is a major challenge that causes marked variation in individual response rate and survival rate. In this study, we aimed to identify the expression of GTSE1 and its co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Subhash, Vinod Vijay, Tan, Shi Hui, Tan, Woei Loon, Yeo, Mei Shi, Xie, Chen, Wong, Foong Ying, Kiat, Zee Ying, Lim, Robert, Yong, Wei Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514980/ https://www.ncbi.nlm.nih.gov/pubmed/26209226 http://dx.doi.org/10.1186/s12885-015-1550-0

Ejemplares similares

Strategies and Advancements in Harnessing the Immune System for Gastric Cancer Immunotherapy
por: Subhash, Vinod Vijay, et al.
Publicado: (2015)

Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor
por: Subhash, Vinod Vijay, et al.
Publicado: (2018)

GTSE1 is possibly involved in the DNA damage repair and cisplatin resistance in osteosarcoma
por: Xie, Chaofan, et al.
Publicado: (2021)

Pan-cancer analyses reveal GTSE1 as a biomarker for the immunosuppressive tumor microenvironment
por: Tan, Ke, et al.
Publicado: (2023)

High GTSE1 expression promotes cell proliferation, metastasis and cisplatin resistance in ccRCC and is associated with immune infiltrates and poor prognosis
por: Lei, Pu, et al.
Publicado: (2023)

GTSE1 promotes the growth of NSCLC by regulating microtubule‐associated proteins through the ERK/MAPK pathway
por: Wang, Chuanlin, et al.
Publicado: (2023)

Silencing GTSE-1 expression inhibits proliferation and invasion of hepatocellular carcinoma cells
por: Guo, Lei, et al.
Publicado: (2016)

GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner
por: Lin, Fen, et al.
Publicado: (2019)

FBXW5 Promotes Tumorigenesis and Metastasis in Gastric Cancer via Activation of the FAK-Src Signaling Pathway
por: Yeo, Mei Shi, et al.
Publicado: (2019)

GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK
por: Bendre, Shweta, et al.
Publicado: (2016)

GTSE1 promotes cell migration and invasion by regulating EMT in hepatocellular carcinoma and is associated with poor prognosis
por: Wu, Xiaojuan, et al.
Publicado: (2017)

GTSE1, CDC20, PCNA, and MCM6 Synergistically Affect Regulations in Cell Cycle and Indicate Poor Prognosis in Liver Cancer
por: Zheng, Yongchang, et al.
Publicado: (2019)

GTSE1 Is a Microtubule Plus-End Tracking Protein That Regulates EB1-Dependent Cell Migration
por: Scolz, Massimilano, et al.
Publicado: (2012)

GTSE1 promotes SNAIL1 degradation by facilitating its nuclear export in hepatocellular carcin oma cells
por: Li, Shan-Shan, et al.
Publicado: (2021)

GTSE1 Facilitates the Malignant Phenotype of Lung Cancer Cells via Activating AKT/mTOR Signaling
por: Zhang, Fan, et al.
Publicado: (2021)

Knockdown GTSE1 enhances radiosensitivity in non–small‐cell lung cancer through DNA damage repair pathway
por: Lei, Xiao, et al.
Publicado: (2020)

Defining endogenous TACC3–chTOG–clathrin–GTSE1 interactions at the mitotic spindle using induced relocalization
por: Ryan, Ellis L., et al.
Publicado: (2021)

GTSE1 regulates spindle microtubule dynamics to control Aurora B kinase and Kif4A chromokinesin on chromosome arms
por: Tipton, Aaron R., et al.
Publicado: (2017)

Down‐regulation of miR‐26b induces cisplatin resistance in nasopharyngeal carcinoma by repressing JAG1
por: Shi, Lei, et al.
Publicado: (2016)

Computational modeling of apoptotic signaling pathways induced by cisplatin
por: Hong, Ji-Young, et al.
Publicado: (2012)

Cordycepin enhances cisplatin apoptotic effect through caspase/MAPK pathways in human head and neck tumor cells
por: Chen, Ying-Hui, et al.
Publicado: (2013)

circ_AKT3 knockdown suppresses cisplatin resistance in gastric cancer
por: Shi, Wenting, et al.
Publicado: (2022)

Downregulation of Mcl-1 synergizes the apoptotic response to combined treatment with cisplatin and a novel fiber chimeric oncolytic adenovirus
por: YOU, LIANGSHUN, et al.
Publicado: (2012)

GTSE1: a novel TEAD4-E2F1 target gene involved in cell protrusions formation in triple-negative breast cancer cell models
por: Stelitano, Debora, et al.
Publicado: (2017)

Data mining and big data: 4th international conference, DMBD 2019, Chiang Mai, Thailand, July 26-30, 2019, proceedings
por: Tan, Ying, et al.
Publicado: (2019)

Sinomenine sensitizes human gastric cancer cells to cisplatin through negative regulation of PI3K/AKT/Wnt signaling pathway
por: Liu, Ying, et al.
Publicado: (2019)

Metformin potentiates rapamycin and cisplatin in gastric cancer in mice
por: Yu, Yu, et al.
Publicado: (2015)

Institute of Industrial Engineers Asian Conference 2013
por: Lin, Yi-Kuei, et al.
Publicado: (2013)

HIF-1α-dependent miR-424 induction confers cisplatin resistance on bladder cancer cells through down-regulation of pro-apoptotic UNC5B and SIRT4
por: Yu, Meng, et al.
Publicado: (2020)

Data mining and big data: third international conference, DMBD 2018, Shanghai, China, June 17-22, 2018, proceedings
por: Tan, Ying, et al.
Publicado: (2018)

Multiple mechanisms repress N-Bak mRNA translation in the healthy and apoptotic neurons
por: Jakobson, M, et al.
Publicado: (2013)

Data mining and big data: second international conference, DMBD 2017, Fukuoka, Japan, July 27 - August 1, 2017, proceedings
por: Tan, Ying, et al.
Publicado: (2017)

Epidemiology and Prognosis of Paraneoplastic Syndromes in Hepatocellular Carcinoma
por: Chang, Pik Eu, et al.
Publicado: (2013)

Let-7e sensitizes epithelial ovarian cancer to cisplatin through repressing DNA double strand break repair
por: Xiao, Man, et al.
Publicado: (2017)

Advances in swarm intelligence: 9th international conference, ICSI 2018, Shanghai, China, June 17-22, 2018, proceedings, part I
por: Tan, Ying, et al.
Publicado: (2018)

miR-187/PDLIM1 Gets Involved in Gastric Cancer Progression and Cisplatin Sensitivity of Cisplatin by Mediating the Hippo-YAP Signaling Pathway
por: Tan, Yeru, et al.
Publicado: (2022)

Smad3 Sensitizes Hepatocelluar Carcinoma Cells to Cisplatin by Repressing Phosphorylation of AKT
por: Zhou, Hong-Hao, et al.
Publicado: (2016)

The Modulation of Apoptotic Pathways by Gammaherpesviruses
por: Banerjee, Shuvomoy, et al.
Publicado: (2016)

Advances in swarm intelligence: 10th international conference, ICSI 2019, Chiang Mai, Thailand, July 26-30, 2019, proceedings, part I
por: Tan, Ying, et al.
Publicado: (2019)

Advances in swarm intelligence: 8th international conference, ICSI 2017, Fukuoka, Japan, July 27 - August 1, 2017, proceedings, part I
por: Tan, Ying, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_h3grnafiuu49ri2ht40h8egumq