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Autoregulatory function of interleukin-10-producing pre-naïve B cells is defective in systemic lupus erythematosus

INTRODUCTION: Pre-naïve B cells represent an intermediate stage in human B-cell development with some functions of mature cells, but their involvement in immune responses is unknown. The aim of this study was to determine the functional role of normal pre-naïve B cells during immune responses and po...

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Detalles Bibliográficos
Autores principales: Sim, Ji Hyun, Kim, Hang-Rae, Chang, Soog-Hee, Kim, In Je, Lipsky, Peter E., Lee, Jisoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515025/
https://www.ncbi.nlm.nih.gov/pubmed/26209442
http://dx.doi.org/10.1186/s13075-015-0687-1