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Prion-like transmission of neuronal huntingtin aggregates to phagocytic glia in the Drosophila brain
The brain has a limited capacity to self-protect against protein aggregate-associated pathology, and mounting evidence supports a role for phagocytic glia in this process. We have established a Drosophila model to investigate the role of phagocytic glia in clearance of neuronal mutant huntingtin (Ht...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515032/ https://www.ncbi.nlm.nih.gov/pubmed/25866135 http://dx.doi.org/10.1038/ncomms7768 |