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Statin-induced calcification in human mesenchymal stem cells is cell death related

Statins are widely used in clinics to lower cholesterol levels. Recently, they have been shown to positively affect bone formation and bone mass in a rat model. The aim of this study was to investigate the effect of pravastatin, simvastatin and lovastatin on the osteoblastic differentiation of human...

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Detalles Bibliográficos
Autores principales: Kupcsik, Laszlo, Meurya, Thomas, Flury, Matthias, Stoddart, Martin, Alini, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515062/
https://www.ncbi.nlm.nih.gov/pubmed/19602044
http://dx.doi.org/10.1111/j.1582-4934.2008.00545.x