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Synergistic promotion of breast cancer cells death by targeting molecular chaperone GRP78 and heat shock protein 70

Heat shock protein 70 (HSP70) is frequently overexpressed in a variety of human malignancies and protects cancer cells against apoptosis in response to various stresses. The bioflavonoid quercetin inhibits HSP70 expression and induces cancer cells apoptosis. In the present study, we have investigate...

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Detalles Bibliográficos
Autores principales: Li, Minjing, Wang, Jiao, Jing, Jian, Hua, Hui, Luo, Ting, Xu, Li, Wang, Ranran, Liu, Dongbo, Jiang, Yangfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515069/
https://www.ncbi.nlm.nih.gov/pubmed/19017364
http://dx.doi.org/10.1111/j.1582-4934.2008.00575.x