Cargando…

Placebo-Controlled Discontinuation of Long-Term Acid-Suppressant Therapy: A Randomised Trial in General Practice

Objective. To investigate whether patients on long-term antisecretory medication need to continue treatment to control symptoms. Methods. A double-blinded randomised placebo-controlled trial in general practices in Denmark. Patients aged 18–90 who were treated with antisecretory drugs on a long-term...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zwisler, Jon Eik, Jarbøl, Dorte Ejg, Lassen, Annmarie Touborg, Kragstrup, Jakob, Thorsgaard, Niels, Schaffalitzky de Muckadell, Ove B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515283/ https://www.ncbi.nlm.nih.gov/pubmed/26246908 http://dx.doi.org/10.1155/2015/175436

Ejemplares similares

Termination of prehospital resuscitative efforts: a study of documentation on ethical considerations at the scene
por: Mikkelsen, Søren, et al.
Publicado: (2017)

Doppler-Guided Second-Look Endoscopy in Peptic Ulcer Bleeding: A Randomised Controlled Trial
por: Nielsen, Michael Milek, et al.
Publicado: (2023)

Ethical considerations in the prehospital treatment of out-of-hospital cardiac arrest: A multi-centre, qualitative study
por: Milling, Louise, et al.
Publicado: (2023)

Non-medical factors in prehospital resuscitation decision-making: a mixed-methods systematic review
por: Milling, Louise, et al.
Publicado: (2022)

Urological symptoms among 23,240 men in the general danish population – concerns about symptoms, their persistence and influence on primary care contacts
por: Solvang, Majken, et al.
Publicado: (2018)

Statin Discontinuation and Cardiovascular Events Among Older People in Denmark
por: Thompson, Wade, et al.
Publicado: (2021)

IgG4-Related Sclerosing Cholangitis Involving the Intrahepatic Bile Ducts Diagnosed with Liver Biopsy
por: Thinesen, Malene Theilmann, et al.
Publicado: (2018)

Gene Expression Network Analysis of Precursor Lesions in Familial Pancreatic Cancer
por: Tan, Ming, et al.
Publicado: (2020)

Management of Overweight during Childhood: A Focus Group Study on Health Professionals' Experiences in General Practice
por: Larsen, Lone Marie, et al.
Publicado: (2015)

The effect of chiropractic care on infantile colic: results from a single-blind randomised controlled trial
por: Holm, Lise Vilstrup, et al.
Publicado: (2021)

Documentation of ethically relevant information in out-of-hospital resuscitation is rare: a Danish nationwide observational study of 16,495 out-of-hospital cardiac arrests
por: Milling, Louise, et al.
Publicado: (2021)

Response to Letter to the Editor: “The effect of chiropractic care on infantile colic: results from a single-blind randomised controlled trial” and “Identifying potential treatment effect modifiers of the effectiveness of chiropractic care to infants with colic through prespecified secondary analyses of a randomised controlled trial”
por: Hestbæk, Lise, et al.
Publicado: (2021)

Healthcare practices that increase the quality of care in cancer trajectories from a general practice perspective: a scoping review
por: Nicolaisen, Anne, et al.
Publicado: (2022)

Early intervention for childhood overweight: A randomized trial in general practice
por: Larsen, Lone Marie, et al.
Publicado: (2015)

Prediction of overt hepatic encephalopathy by the continuous reaction time method and the portosystemic encephalopathy syndrome test in clinically mentally unimpaired patients with cirrhosis
por: Wernberg, Charlotte W., et al.
Publicado: (2019)

Identifying potential treatment effect modifiers of the effectiveness of chiropractic care to infants with colic through prespecified secondary analyses of a randomised controlled trial
por: Holm, Lise Vilstrup, et al.
Publicado: (2021)

Lifestyle factors and experience of respiratory alarm symptoms in the general population
por: Sele, Lisa Maria Falk, et al.
Publicado: (2015)

Women’s barriers for contacting their general practitioner when bothered by urinary incontinence: a population-based cross-sectional study
por: Jarbøl, Dorte Ejg, et al.
Publicado: (2021)

Impact of effectiveness information format on patient choice of therapy and satisfaction with decisions about chronic disease medication: the "Influence of intervention Methodologies on Patient Choice of Therapy (IMPACT)" cluster-randomised trial in general practice
por: Harmsen, Charlotte Gry, et al.
Publicado: (2013)

Socioeconomic status and barriers for contacting the general practitioner when bothered by erectile dysfunction: a population-based cross-sectional study
por: Rasmussen, Sanne, et al.
Publicado: (2020)

Value of anti-plasminogen binding peptide, anti-carbonic anhydrase II, immunoglobulin G4, and other serological markers for the differentiation of autoimmune pancreatitis and pancreatic cancer
por: Detlefsen, Sönke, et al.
Publicado: (2018)

Lifestyle factors and contact to general practice with respiratory alarm symptoms—a population-based study
por: Sele, Lisa Maria Falk, et al.
Publicado: (2016)

Comment on ‘Evaluation of the Reported Rates of Severe Hypersensitivity Reactions Associated with Ferric Carboxymaltose and Iron(III) Isomaltoside 1000 in Europe Based on Data from EudraVigilance and VigiBase™ Between 2014 and 2017’
por: Schaffalitzky de Muckadell, Philip, et al.
Publicado: (2019)

Comment on ‘Reported Severe Hypersensitivity Reactions after Intravenous Iron Administration in the European Economic Area (EEA) Before and After Implementation of Risk Minimization Measures’
por: Schaffalitzky de Muckadell, Philip, et al.
Publicado: (2020)

Prognosis and Risk Factors for Deterioration in Patients Admitted to a Medical Emergency Department
por: Henriksen, Daniel Pilsgaard, et al.
Publicado: (2014)

Enhanced involvement of general practitioners in cancer rehabilitation: a randomised controlled trial
por: Bergholdt, Stinne Holm, et al.
Publicado: (2012)

Low Back Pain in Primary Care: A Description of 1250 Patients with Low Back Pain in Danish General and Chiropractic Practice
por: Hestbaek, Lise, et al.
Publicado: (2014)

Is healthcare-seeking with gynaecological alarm symptoms influenced by personal and professional relations? A Danish population-based, cross-sectional study
por: Vejlgaard, Anja Schmidt, et al.
Publicado: (2020)

A randomised controlled trial to improve the role of the general practitioner in cancer rehabilitation: effect on patients’ satisfaction with their general practitioners
por: Bergholdt, Stinne Holm, et al.
Publicado: (2013)

Women’s barriers for contacting general practice when experiencing gynecological cancer symptoms: a population-based study
por: Balasubramaniam, Kirubakaran, et al.
Publicado: (2021)

Timing of antibiotic treatment among infected patients with- and without fever - a prospective cohort study in a medical emergency department
por: Henriksen, Daniel Pilsgaard, et al.
Publicado: (2013)

Seven-Day Mortality Can Be Predicted in Medical Patients by Blood Pressure, Age, Respiratory Rate, Loss of Independence, and Peripheral Oxygen Saturation (the PARIS Score): A Prospective Cohort Study with External Validation
por: Brabrand, Mikkel, et al.
Publicado: (2015)

Multiple perspectives on symptom interpretation in primary care research
por: Rosendal, Marianne, et al.
Publicado: (2013)

Spirometry in Greenland: a cross-sectional study on patients treated with medication targeting obstructive pulmonary disease
por: Nielsen, Lasse Overballe, et al.
Publicado: (2016)

Activation of professional and personal network relations when experiencing a symptom: a population-based cross-sectional study
por: Elnegaard, Sandra, et al.
Publicado: (2017)

Associations between smoking status and involvement of personal and professional relations among individuals reporting symptoms related to a diagnosis of lung cancer: a population-based study
por: Vognsgaard, Frederik, et al.
Publicado: (2022)

Associations between lifestyle, erectile dysfunction and healthcare seeking: a population-based study
por: Paulsen, Louise Herluf, et al.
Publicado: (2020)

Splenomegaly – Diagnostic validity, work-up, and underlying causes
por: Curovic Rotbain, Emelie, et al.
Publicado: (2017)

Validation of a Simple Quality‐of‐Life Score for Identification of Minimal and Prediction of Overt Hepatic Encephalopathy
por: Lauridsen, Mette Munk, et al.
Publicado: (2020)

Dealing with symptoms in the general population: lessons learned from the Danish Symptom Cohort
por: Balasubramaniam, Kirubakaran, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8s4pt8peoh3rimnldmsgn1ctj4